Factory Direct Sales HPE ProLiant DL345 Gen11 HPE ProLiant DL345 Gen10 Plus server 2U Rack Server

Here’s a detailed comparison table for the HPE ProLiant DL345 Gen11 and DL345 Gen10 Plus servers:
HPE ProLiant DL345 Gen11 vs DL345 Gen10 Plus Comparison Table
| Feature | DL345 Gen11 | DL345 Gen10 Plus |
|---|---|---|
| Form Factor | 1U Rack Server | 1U Rack Server |
| Processor | AMD EPYC 9004 (Genoa) | AMD EPYC 7003 (Milan) |
| Max Cores/Threads | Up to 96C/192T | Up to 64C/128T |
| Memory | 12× DDR5 DIMMs (Up to 3TB) | 16× DDR4 DIMMs (Up to 4TB) |
| Storage | 10× SFF or 4× LFF bays | 12× SFF or 4× LFF bays |
| PCIe Expansion | 4× Gen5 (x16/x16/x16/x8) | 3× Gen4 (x16/x16/x8) |
| GPU Support | 3× Single-Wide (225W each) | 2× Single-Wide (150W each) |
| Drive Bays | 10× 2.5″ or 4× 3.5″ | 12× 2.5″ or 4× 3.5″ |
| Networking | 2× 1GbE + OCP 3.0 | 2× 1GbE + OCP 2.0 |
| Power Supply | Dual 1400W (Platinum) | Dual 800W (Gold) |
| Remote Management | iLO 6 | iLO 5 |
| Security | Silicon Root of Trust v2 | Silicon Root of Trust |
| Ideal Workloads | AI Training, HPC | Virtualization, Cloud |
1. HPE ProLiant DL345 Gen11: AI-Ready Powerhouse
Built For: Next-generation AI training and hyperscale workloads
Key Innovation: AMD EPYC 9004 (Genoa) with PCIe Gen5 and DDR5
Breakthrough Capabilities:
- Processor: Up to 96 cores/192 threads (Zen 4 architecture)
- Memory: 12× DDR5 DIMMs (3TB, 4800MHz) with AMD Secure Memory Encryption
- Acceleration:
- 4× PCIe Gen5 slots (3× x16 + 1× x8)
- Triple 225W GPU support (e.g., NVIDIA L40S or AMD Instinct MI250X)
- Storage: 10× 2.5″ NVMe bays (4× 3.5″ HDD alternative)
Enterprise-Grade Features:
✔ 1400W Platinum PSUs (96% efficiency)
✔ OCP 3.0 with 200GbE networking support
✔ iLO 6 with cloud-based AIOps monitoring
Best For:
- Large language model (LLM) training
- 3D rendering farms
- High-frequency trading systems
2. HPE ProLiant DL345 Gen10 Plus: Proven Virtualization Champion
Built For: Memory-intensive traditional workloads
Key Strength: Balanced performance with higher memory capacity
Optimized Configuration:
- Processor: AMD EPYC 7003 (Up to 64C/128T, Zen 3)
- Memory: 16× DDR4 DIMMs (4TB max) – More capacity than Gen11
- Storage: 12× 2.5″ bays (or 4× 3.5″) with hardware RAID options
- Expansion:
- 3× PCIe Gen4 slots
- Dual 150W GPUs (e.g., NVIDIA A2 or AMD Instinct MI100)
Cost-Effective Advantages:
✔ 800W Gold PSUs (lower power draw)
✔ iLO 5 with legacy system compatibility
✔ Higher drive bay count than Gen11
Best For:
- Virtualized data centers (50+ VMs)
- SAP HANA in-memory databases
- Video surveillance storage (100+ camera feeds)
Technical Comparison
| Feature | DL345 Gen11 | DL345 Gen10 Plus |
|---|---|---|
| CPU Architecture | Zen 4 (5nm) | Zen 3 (7nm) |
| PCIe Bandwidth | 512GB/s (Gen5) | 256GB/s (Gen4) |
| GPU Power Budget | 675W total | 300W total |
| NVMe Support | Gen5 NVMe (14GB/s per drive) | Gen4 NVMe (7GB/s per drive) |
| Typical Use | AI/ML clusters | Private cloud infrastructure |
Shared AMD Platform Benefits:
- 1U dense form factor (43mm height)
- AMD Infinity Guard security suite
- Support for all major hypervisors
Upgrade Considerations:
- Gen11 delivers 2.1× better AI training performance
- Gen10 Plus offers 30% better $/GB memory cost
Management Tools:
- Both support HPE GreenLake hybrid cloud
- Common HPE OneView management interface









