Professional High Quality New HPE ProLiant Compute DL380 Gen12 DL380a DL384 Gen12 Rack Server
Here’s a detailed comparison table for the HPE ProLiant DL380 Gen12, DL380a Gen12, and DL384 Gen12 servers:
| Feature | DL380 Gen12 (Intel) | DL380a Gen12 (AMD) | DL384 Gen12 (Hybrid) |
|---|---|---|---|
| Processor | Intel Xeon Scalable 4th/5th Gen | AMD EPYC 9004 Series | Intel Xeon Scalable 4th/5th Gen + AMD Instinct |
| Max Sockets | 2 | 2 | 2 |
| Max Cores | Up to 128 (64/socket) | Up to 192 (96/socket) | Up to 128 + GPU cores |
| Memory | DDR5, 6TB (32 DIMMs) | DDR5, 6TB (32 DIMMs) | DDR5, 6TB + HBM (GPU) |
| PCIe Version | PCIe 5.0 | PCIe 5.0 | PCIe 5.0 + CXL 2.0 |
| Storage | 32x SFF or 12x LFF | 32x SFF or 12x LFF | 24x SFF + 4x GPU NVLink |
| GPU Support | Up to 4x GPUs | Up to 4x GPUs | Up to 6x GPUs (NVIDIA/AMD) |
| Accelerator Options | Intel Flex Series | AMD Instinct MI300 | Both Intel/AMD + FPGA |
| Network | OCP 3.0, 200GbE | OCP 3.0, 200GbE | OCP 3.0 + Quantum-2 |
| Power | 1600W Titanium (94%) | 1600W Titanium (94%) | 2000W Liquid-Cooled |
| Security | iLO 6 + Silicon Root of Trust | iLO 6 + AMD Secure Processor | iLO 6 + Dual Root of Trust |
| Cooling | Air/Liquid-ready | Air/Liquid-ready | Direct Liquid Cooling |
| Use Cases | Enterprise Virtualization | HPC/AI Workloads | Hybrid Cloud AI |
| Unique Feature | Intel AMX Instructions | AMD 3D V-Cache | Unified CPU/GPU Memory Pool |
HPE ProLiant Compute DL380 Gen12
The HPE ProLiant DL380 Gen12 is a flagship 2U dual-socket server powered by 4th/5th Gen Intel® Xeon® Scalable processors, delivering up to 128 cores and 6TB of DDR5 memory. Designed for mission-critical enterprise workloads, it excels in virtualization (VMware, Hyper-V), databases (SQL, Oracle), and private cloud deployments.
With PCIe 5.0 support (32 lanes per CPU), the DL380 Gen12 offers up to 4x GPUs (NVIDIA H100/A100) or 32x SFF/12x LFF drives for high-density storage. It features HPE iLO 6 with Silicon Root of Trust for advanced security and 1600W Titanium PSUs (94% efficiency).
Key Innovations:
- Intel AMX for AI acceleration
- Liquid-cooling ready for dense deployments
- OCP 3.0 200GbE networking
Best for: SAP HANA, enterprise virtualization, and traditional data center workloads.
HPE ProLiant Compute DL380a Gen12
The HPE ProLiant DL380a Gen12 is a 2U AMD EPYC™-based powerhouse built for core-intensive and technical computing. Featuring AMD EPYC 9004 Series processors, it scales to 192 cores and 6TB DDR5, offering superior performance-per-dollar for Linux/AI workloads.
Optimized for HPC and AI training, it supports PCIe 5.0, 4x GPUs (AMD Instinct MI300/NVIDIA H100), and the same storage flexibility as the Intel variant (32x SFF/12x LFF). The AMD Secure Processor and iLO 6 provide robust security.
Key Advantages:
- AMD 3D V-Cache for low-latency workloads
- Higher core density vs. Intel counterparts
- Energy-efficient design (1600W Titanium PSUs)
Best for: Scientific computing, AI/ML, and scale-out cloud environments.
HPE ProLiant Compute DL384 Gen12
The HPE ProLiant DL384 Gen12 is a hybrid-architecture 2U server combining Intel Xeon Scalable CPUs with AMD Instinct GPUs for unified AI/ML pipelines. It supports up to 128 CPU cores + 6x GPUs with shared HBM memory, eliminating data bottlenecks.
Designed for generative AI and hybrid cloud, it features:
- PCIe 5.0 + CXL 2.0 for CPU-GPU coherence
- Direct liquid cooling (2000W capacity)
- Quantum-2 networking for low-latency clusters
Unique Capabilities:
- Unified memory pool between CPUs/GPUs
- FPGA support for customizable acceleration
- Dual Root of Trust (Intel + AMD)
Best for: Large language models (LLMs), real-time AI inference, and heterogeneous computing.
Comparison Summary
| Aspect | DL380 Gen12 (Intel) | DL380a Gen12 (AMD) | DL384 Gen12 (Hybrid) |
|---|---|---|---|
| CPU | Xeon Scalable (128 cores) | EPYC 9004 (192 cores) | Xeon + AMD Instinct |
| Memory | 6TB DDR5 | 6TB DDR5 | 6TB DDR5 + GPU HBM |
| GPU Support | 4x (NVIDIA/Intel) | 4x (NVIDIA/AMD) | 6x (Unified memory) |
| Use Case | Enterprise apps | HPC/AI | Generative AI |
| Price Range | 15K–60K | 12K–50K | 25K–120K+ |
Choosing the Right Server:
- DL380 Gen12: Traditional data centers needing Intel ecosystem.
- DL380a Gen12: Cost-sensitive HPC/AI with AMD’s core advantage.
- DL384 Gen12: Cutting-edge AI with CPU-GPU memory pooling.
