High Performance HHPE ProLiant DL385 Gen11 HPE ProLiant DL385 Gen10 Plus v2 server 32GB 8SFF 800W PS Computer Server
Here’s a detailed comparison table between the HPE ProLiant DL385 Gen11 and HPE ProLiant DL385 Gen10 Plus v2 servers:
HPE ProLiant DL385 Gen11 vs. DL385 Gen10 Plus v2 Comparison Table
| Feature | HPE ProLiant DL385 Gen11 | HPE ProLiant DL385 Gen10 Plus v2 |
|---|---|---|
| Generation | Gen11 (2023) | Gen10 Plus Refresh (2022) |
| Processor | AMD EPYC™ 9004 Series (Genoa/Bergamo) | AMD EPYC™ 7003 Series (Milan) |
| Max Cores | Up to 192 cores (EPYC 9654) | Up to 128 cores (EPYC 7763) |
| CPU Architecture | Zen 4 (5nm) | Zen 3 (7nm) |
| Memory | DDR5, Up to 6TB (32 DIMMs) | DDR4, Up to 4TB (32 DIMMs) |
| Memory Speed | Up to 4800 MHz | Up to 3200 MHz |
| PCIe Support | PCIe 5.0Â (Up to 128 lanes) | PCIe 4.0Â (Up to 128 lanes) |
| Storage Options | Up to 32x SFF or 12x LFF | Up to 32x SFF or 12x LFF |
| GPU Support | NVIDIA H100, AMD Instinct MI300 | NVIDIA A100, AMD Instinct MI200 |
| Network Options | 100/200GbE SmartNICs, OCP 3.0 | 25/100GbE, OCP 2.0 |
| Power Supplies | 800W/1600W Titanium (High efficiency) | 800W/1600W Platinum |
| Security Features | Silicon Root of Trust, iLO 6 | Secure Boot, iLO 5 |
| Cooling Efficiency | Liquid-cooling ready (Advanced airflow) | Air-cooled (Standard) |
| Use Case Focus | AI/ML, HPC, Cloud-native apps | Virtualization, Databases, Enterprise workloads |
| Release Year | 2023 | 2022 |
HPE ProLiant DL385 Gen11 Server
The HPE ProLiant DL385 Gen11 is a next-generation 2U AMD-powered server designed for high-performance computing (HPC), AI/ML, and cloud-native workloads. It features AMD EPYC™ 9004 Series processors (Genoa/Bergamo), delivering up to 192 cores and 384 threads—making it one of the most powerful dual-socket servers available.
Built on Zen 4 architecture (5nm process), the DL385 Gen11 supports DDR5 memory (up to 6TB at 4800MHz) and PCIe 5.0, doubling bandwidth over Gen10 servers for faster GPU and NVMe storage performance. It offers up to 32x SFF or 12x LFF drive bays, along with support for NVIDIA H100 and AMD Instinct MI300 accelerators, making it ideal for AI training and inference.
Security and manageability are enhanced with HPE iLO 6 and Silicon Root of Trust, ensuring secure boot and firmware integrity. The server also supports liquid cooling for improved thermal efficiency in dense data centers.
Ideal for:Â AI/ML, hyperscale cloud, HPC, and enterprise virtualization.
HPE ProLiant DL385 Gen10 Plus v2 Server
The HPE ProLiant DL385 Gen10 Plus v2 is a cost-effective, high-density AMD EPYC server that bridges the gap between Gen10 and Gen11. It features AMD EPYC 7003 Series (Milan) processors, offering up to 128 cores and 256 threads, with DDR4 memory (up to 4TB at 3200MHz) and PCIe 4.0 support.
While slightly older than Gen11, the Gen10 Plus v2 remains a strong performer for virtualization, databases, and enterprise applications. It supports up to 32x SFF or 12x LFF drives and is compatible with NVIDIA A100 and AMD Instinct MI200 GPUs, making it suitable for GPU-accelerated workloads.
Security features include HPE iLO 5 for remote management and Secure Boot for firmware protection. The server uses Platinum efficiency power supplies (800W/1600W) and is optimized for air-cooled environments.
Ideal for:Â Enterprise workloads, virtualized environments, and mid-range AI/GPU computing.
Key Differences Summary
| Aspect | DL385 Gen11 | DL385 Gen10 Plus v2 |
|---|---|---|
| CPU | AMD EPYC 9004 (Zen 4, up to 192 cores) | AMD EPYC 7003 (Zen 3, up to 128 cores) |
| Memory | DDR5 (6TB, 4800MHz) | DDR4 (4TB, 3200MHz) |
| PCIe Version | PCIe 5.0 (2x bandwidth) | PCIe 4.0 |
| GPU Support | NVIDIA H100, AMD MI300 | NVIDIA A100, AMD MI200 |
| Security | iLO 6, Silicon Root of Trust | iLO 5, Secure Boot |
| Cooling | Liquid-cooling ready | Air-cooled |
| Best For | AI, HPC, cloud-native | Virtualization, enterprise workloads |
Which One Should You Choose?
- DL385 Gen11 → Best for cutting-edge AI, HPC, and future-proofing with PCIe 5.0 and DDR5.
- DL385 Gen10 Plus v2 → A budget-friendly option for enterprise virtualization and GPU workloads where PCIe 4.0 is sufficient.
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