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HPE ProLiant DL380 Gen11 Gen10 DL380a Gen11 DL380 Gen10 Plus server with 64GB DDR5 2.8GHz Intel Processor 800W Power Best Price for SQL Server

$999.00$6,800.00

  • Gen11 (DL380 Gen11 & DL380a Gen11) → Latest tech (DDR5, PCIe 5.0, 4th/5th Gen Intel or AMD EPYC 9004).
  • DL380a Gen11 → AMD-based alternative to Intel DL380 Gen11.
  • Gen10 Plus → A mid-life refresh with PCIe 4.0 and 3rd Gen Intel Xeon.
  • Gen10 (Original) → Older, limited to PCIe 3.0 and lower core counts.
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HPE ProLiant DL380 Gen11 Gen10 DL380a Gen11 DL380 Gen10 Plus server with 64GB DDR5 2.8GHz Intel Processor 800W Power Best Price for SQL Server

Here’s a comparison table for the HPE ProLiant DL380 Gen11, DL380 Gen10, DL380a Gen11, and DL380 Gen10 Plus servers:

Feature HPE ProLiant DL380 Gen11 HPE ProLiant DL380 Gen10 HPE ProLiant DL380a Gen11 HPE ProLiant DL380 Gen10 Plus
Generation Gen11 (2023) Gen10 (2017) Gen11 (2023) Gen10 Plus (2021)
Processor Intel® Xeon® Scalable 4th/5th Gen (Emerald Rapids/Sierra Forest) Intel® Xeon® Scalable 1st/2nd Gen (Skylake/Cascade Lake) AMD EPYC™ 9004 Series (Genoa/Bergamo) Intel® Xeon® Scalable 3rd Gen (Ice Lake)
Max Cores Up to 128 (with 5th Gen) Up to 56 (with 2nd Gen) Up to 192 (with EPYC 9654) Up to 80 (with Xeon Platinum 8380)
Memory DDR5, Up to 6TB (32 DIMMs) DDR4, Up to 3TB (24 DIMMs) DDR5, Up to 6TB (32 DIMMs) DDR4, Up to 6TB (32 DIMMs)
Storage Options Up to 32x SFF or 12x LFF Up to 28x SFF or 12x LFF Up to 32x SFF or 12x LFF Up to 32x SFF or 12x LFF
PCIe Slots PCIe 5.0 (Up to 8 slots) PCIe 3.0 (Up to 8 slots) PCIe 5.0 (Up to 8 slots) PCIe 4.0 (Up to 8 slots)
GPU Support NVIDIA H100, AMD Instinct MI300 NVIDIA T4, A100 (limited) NVIDIA H100, AMD Instinct MI300 NVIDIA A100, T4
Network Options HPE Smart NICs, 100GbE 10/25/100GbE options HPE Smart NICs, 100GbE 10/25/100GbE options
Power Supplies 800W/1600W (Titanium) 500W/800W/1600W (Platinum) 800W/1600W (Titanium) 800W/1600W (Platinum)
Security Features Silicon Root of Trust, HPE Integrated Lights-Out 6 (iLO 6) iLO 5, Secure Boot Silicon Root of Trust, iLO 6 iLO 5, Secure Recovery
Use Case AI, HPC, Virtualization General Enterprise Cloud, AI, HPC High-Performance Workloads
Release Year 2023 2017 2023 2021

HPE ProLiant DL380 Gen11

The HPE ProLiant DL380 Gen11 is HPE’s latest flagship 2U rack server, designed for high-performance workloads, AI, and modern data center demands. It supports 4th and 5th Gen Intel Xeon Scalable processors (Emerald Rapids/Sierra Forest), offering up to 128 cores and DDR5 memory (up to 6TB). With PCIe 5.0 support, it delivers double the bandwidth of Gen10 servers, making it ideal for AI/ML workloads with GPUs like NVIDIA H100 or AMD Instinct MI300. Storage flexibility includes up to 32x SFF or 12x LFF drives, while HPE iLO 6 enhances security with Silicon Root of Trust. This server is optimized for virtualization, databases, and high-performance computing (HPC).

Best for: AI, enterprise virtualization, high-density cloud workloads.


HPE ProLiant DL380 Gen10

The HPE ProLiant DL380 Gen10 is a proven 2U enterprise workhorse, supporting 1st and 2nd Gen Intel Xeon Scalable processors (Skylake/Cascade Lake) with up to 56 cores and DDR4 memory (3TB max). While older, it remains reliable for general-purpose workloads with PCIe 3.0 expansion and support for NVIDIA T4/A100 GPUs. Storage options include up to 28x SFF or 12x LFF drives, and it features HPE iLO 5 for remote management. Though surpassed by newer generations, it’s still widely used in traditional data centers.

Best for: General enterprise applications, virtualization, and legacy workloads.


HPE ProLiant DL380a Gen11

The HPE ProLiant DL380a Gen11 is the AMD-powered counterpart to the DL380 Gen11, featuring AMD EPYC 9004 Series processors (Genoa/Bergamo) with up to 192 cores—making it ideal for core-intensive cloud and HPC workloads. Like the Intel-based Gen11, it supports DDR5 memory (6TB max), PCIe 5.0, and high-end GPUs (NVIDIA H100, AMD Instinct MI300). Storage options match the DL380 Gen11 (32x SFF or 12x LFF), and it includes HPE iLO 6 for advanced security. This server excels in cloud-native apps, AI training, and scale-out environments.

Best for: Cloud service providers, AI/ML, and high-core-count workloads.


HPE ProLiant DL380 Gen10 Plus

The HPE ProLiant DL380 Gen10 Plus is an enhanced version of the Gen10, bridging the gap between Gen10 and Gen11. It supports 3rd Gen Intel Xeon Scalable (Ice Lake) with up to 80 cores and 6TB DDR4 memory. Featuring PCIe 4.0 (a step up from Gen10’s PCIe 3.0), it supports NVIDIA A100 GPUs and offers up to 32x SFF or 12x LFF storage. It retains HPE iLO 5 and is a cost-effective upgrade for users needing better performance than Gen10 without moving to Gen11.

Best for: Mid-range virtualization, databases, and GPU-accelerated workloads.


Summary of Key Differences:

  • Performance: Gen11 (DL380/DL380a) > Gen10 Plus > Gen10
  • CPU Options: Intel (Gen11/Gen10 Plus/Gen10) vs. AMD (DL380a Gen11)
  • PCIe Support: Gen11 (PCIe 5.0) > Gen10 Plus (PCIe 4.0) > Gen10 (PCIe 3.0)
  • Memory: DDR5 (Gen11) vs. DDR4 (Gen10/Gen10 Plus)
  • Use Cases: AI/ML (Gen11) vs. general enterprise (Gen10) vs. balanced upgrade (Gen10 Plus)
HPE ProLiant DL380 Gen11

DL380 Gen10, DL380 Gen10 Plus, DL380 Gen11, DL380a Gen11

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